SpotLIGHT ⎪ RESEARCH

Scientific Progress in Smartphone-Based Detection of Strep A: Expanding the Evidence Base

Today, a peer-reviewed pilot study titled “Smartphone-based Detection of Group A Streptococcal Pharyngitis in Ugandan Children” was published in The Pediatric Infectious Disease Journal. a leading pediatric infectious disease journal, contributing to the growing body of scientific literature evaluating the potential role of smartphone-enabled image analysis and machine learning in infectious disease assessment.

The study adds to ongoing academic and clinical interest in whether smartphone-acquired images, paired with computational analysis, may support future approaches to identifying signs associated with Group A Streptococcal (“Strep A”) pharyngitis in care settings.

Importantly, the publication reflects exploratory scientific research and should be understood as contributing to the broader evidence base for investigation of such technologies. The findings are not evidence of regulatory approval, clinical utility, diagnostic efficacy, or commercial readiness of any investigational product, including Light AI’s QuickScan™ Strep A platform.

Light AI believes continued peer-reviewed scientific activity in this field highlights the importance of rigorous clinical validation, prospective evidence generation, and regulatory engagement to evaluate whether investigational technologies may ultimately support future healthcare workflows. The Company remains focused on execution of its clinical, regulatory, and product development plans consistent with applicable regulatory requirements.

Forward-Looking Information

This newsletter contains forward-looking statements and forward-looking information within the meaning of applicable Canadian securities legislation (collectively, “forward-looking statements”), including but not limited to statements regarding the anticipated scope, timing, enrollment, objectives, endpoints, execution, completion, and expected outcomes of the pivotal clinical trial; the Company’s planned FDA submission and regulatory strategy; potential regulatory authorization; anticipated software functionality; future commercialization opportunities; and the Company’s business strategy, development plans, and market opportunities.

Forward-looking statements are based on management’s current expectations, assumptions, and beliefs as of the date of this newsletter and are subject to a number of risks, uncertainties and assumptions that could cause actual results to differ materially from those expressed or implied, including risks relating to clinical trial execution, enrollment and completion, data quality, protocol adherence, regulatory review and outcomes, technology performance, market conditions, financing requirements, intellectual property, commercialization, reimbursement, competition, and general business, economic and capital market conditions.

QuickScan™ Strep A is an investigational product and has not been approved or cleared by the U.S. Food and Drug Administration, Health Canada, or any other regulatory authority for diagnostic use. There can be no assurance that clinical trial results will support a successful FDA submission, regulatory authorization, Health Canada authorization, or commercialization.

Readers are cautioned not to place undue reliance on forward-looking statements. Except as required by applicable law, the Company undertakes no obligation to update or revise forward-looking statements to reflect new events or circumstances.